Dweezil Zappa (born September 5, 1969, in Los Angeles) is a heavy metal guitarist. He's the son of Frank Zappa and the second of four siblings. His father died on December 4, 1993, due to prostate cancer. Dweezil's older sister is Moon Unit, and his two younger siblings are Ahmet and Diva Zappa. Dweezil's registered birth name was Ian Donald Calvin Euclid Zappa, although this only occurred because the hospital at which he was born refused to register him under the name Dweezil. His father instead used the first names of his bandmates to form a name. He was always called Dweezil (pronounced "da weasel") by his family, though, and later had an official name change.

In the mid 1990s, he voiced the character Ajax Duckman on the animated series Duckman.

He dated musician Lisa Loeb for a few years, and the couple starred on television with the show Dweezil & Lisa on Food Network in 2004.

  "On the Spot" (2003) TV Series .... Band leader
Jack Frost (1998/I) .... John Kaplan
Anarchy TV (1998) .... Sid
Duckman (1997) (VG) (voice) .... Ajax
"Duckman: Private Dick/Family Man" (1994) TV Series (voice) .... Ajax
Mother Goose Rock 'n' Rhyme (1990) (TV) .... Special Guest Appearance
"Normal Life" (1990) TV Series .... Jake Harlow
The Running Man (1987) .... Stevie
Heartbeat (1987) (V) .... Band Performer
Pretty in Pink (1986) .... Simon